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Simultaneous Dual Type 2 Biologic Therapy Improves Sinonasal Outcomes in Selected Patients With Chronic Rhinosinusitis With Nasal Polyps

delete2026-08-05
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PRE
AI
F
Friederike Bärhold *
J
Jan Hagemann
E
Eugenio De Corso
A
Anna Sophie Hoffmann
F
Feifei Zhu
P
Patrick Huber
M
Moritz Gröger
U
Ulrike Förster‐Ruhrmann
S
Sietze Reitsma
L
Ludger Klimek
DOI:10.1111/all.70452delete
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Abstract

Abstract

En 中文
Due to the shared underlying pathophysiological mechanism, chronic rhinosinusitis with nasal polyps (CRSwNP) is frequently associated with comorbid systemic type 2 diseases. Rare, complex cases treated simultaneously with two biologics due to inadequate disease control have been reported. The aim of this study was to assess current use of dual biologic therapy in patients with CRSwNP.
Keywords:
biologic
eosinophilic granulomatous polyangiitis
monoclonal antibodies
nasal polyps
type-2 inflammation

Journal

A
Allergy
IF:
12
Papers:
9.3K
Citations:
2.6W

Organization

U
university of amsterdam
Scholars:
5.9W
Papers: 5.1W
Citations: 94
C
charite - universitätsmedizin berlin
Scholars:
190
Papers: 66
Citations: 0
A
a. gemelli universitary hospital foundation
Scholars:
2
Papers: 1
Citations: 0
U
University Medical Center Hamburg-Eppendorf
Scholars:
1.8W
Papers: 1.3W
Citations: 2.0W
C
center for rhinology and allergology
Scholars:
11
Papers: 12
Citations: 0
L
ludwig maximilian university of munich
Scholars:
82
Papers: 45
Citations: 0
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