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Single multimode fiber endoscope

delete2017-01-23
delete130
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Antonio M. Caravaca-Aguirre *
R
Rafael Piestun
DOI:10.1364/OE.25.001656delete
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摘要

摘要

En 中文
Multimode fibers can guide thousands of modes capable of delivering spatial information. Unfortunately, mode dispersion and coupling have so far prevented their use in endoscopic applications. To address this long-lasting challenge, we present a robust scanning fluorescence endoscope. A spatial light modulator shapes the input excitation wavefront to focus light on the distal tip of the fiber and to rapidly scan the focus over the region of interest. A detector array collects the fluorescence emission propagated back from the sample to the proximal tip of the fiber. We demonstrate that proper selection of the multimode fiber is critical for a robust calibration and for high signal-to-background ratio performance. We compare different types of multimode fibers and experimentally show that a focus created through a graded-index fiber can withstand a few millimeters of fiber distal tip translation. The resulting scanning endoscopic microscope images fluorescent samples over a field of view of 80 mu m with a resolution of 2 mu m. (C) 2017 Optical Society of America
Keyword:
OPTICAL-FIBERS
HIGH-RESOLUTION
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期刊

Optics Express 封面图
Optics Express
IF:
3.3
论文数:
6.1W
被引数:
14.3W

机构

University of Colorado System 封面图
University of Colorado System
学者数:
6.3W
论文数: 5.5W
被引数: 1.8K
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