Soft computing in medicine

Ahmet Yardımcı

doi:10.1016/j.asoc.2009.02.003

Soft computing in medicine

2009-06-01

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Ahmet Yardımcı *

DOI：10.1016/j.asoc.2009.02.003

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Soft computing (SC) is not a new term; we have gotten used to reading and hearing about it daily. Nowadays, the term is used often in computer science and information technology. It is possible to define SC in different ways. Nonetheless, SC is a consortium of methodologies which works synergistically and provides, in one form or another, flexible information processing capability for handling real life ambiguous situations. Its aim is to exploit the tolerance for imprecision, uncertainty, approximate reasoning and partial truth in order to achieve tractability, robustness and low-cost solutions. SC includes fuzzy logic (FL), neural networks (NNs), and genetic algorithm (GA) methodologies. SC combines these methodologies as FL and NN (FL-NN), NN and GA (NN-GA) and FL and GA (FL-GA). Recent years have witnessed the phenomenal growth of bio-informatics and medical informatics by using computational techniques for interpretation and analysis of biological and medical data. Among the large number of computational techniques used, SC, which incorporates neural networks, evolutionary computation, and fuzzy systems, provides unmatched utility because of its demonstrated strength in handling imprecise information and providing novel solutions to hard problems. The aim of this paper is to introduce briefly the various SC methodologies and to present various applications in medicine between the years 2000 and 2008. The scope is to demonstrate the possibilities of applying SC to medicine-related problems. The recent published knowledge about use of SC in medicine is researched in MEDLINE. This study detects which methodology or methodologies of SC are used frequently together to solve the special problems of medicine. According to MEDLINE database searches, the rates of preference of SC methodologies in medicine were found as 68% of FL-NN, 27% of NN-GA and 5% of FL-GA. So far, FL-NN methodology was significantly used in medicine. The rates of using FL-NN in clinical science, diagnostic science and basic science were found as %83, %71 and %48, respectively. On the other hand NN-GA and FL-GA methodologies were mostly preferred by basic science of medicine. Another message emerging from this survey is that the number of papers which used NN-GA methodology has continuously risen until today. Also search results put the case clearly that FL-GA methodology has not applied well enough to medicine yet. Undeniable interest in studying SC methodologies in genetics, physiology, radiology, cardiology, and neurology disciplines proves that studying SC is very fruitful in these disciplines and it is expected that future researches in medicine will use SC more than it is used today to solve more complex problems. (C) 2009 Elsevier B.V. All rights reserved.

Keyword:

Soft computing

Fuzzy-neural systems

Fuzzy-genetic algorithms

Neural-genetic algorithms

Medicine

Soft computing in medicine

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