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Speckle reducing OCT using optical chopper
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DOI：10.1364/OE.382369.png)
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摘要
En 中文
Optical coherence tomography (OCT) has been an important and powerful tool for biological research and clinical applications. However, speckle noise significantly degrades the image quality of OCT and has a negative impact on the clinical diagnosis accuracy. In this paper, we propose a novel speckle noise suppression technique which changes the spatial distribution of sample beam using a special optical chopper. Then a series of OCT images with uncorrelated speckle patterns could be captured and compounded to improve the image quality without degradation of resolution. Typical signal-to-noise ratio improvement of similar to 6.4 dB is experimentally achieved in tissue phantom imaging with average number n = 100. Furthermore, compared with conventional OCT, the proposed technique is demonstrated to view finer and clearer biological structures in human skin in vivo, such as sweat glands and blood vessels. The advantages of low cost, simple structure and compact integration will benefit the future design of handheld or endoscopic probe for biomedical imaging in research and clinical applications. (C) 2020 Optical Society of America under the terms of the OSA Open Access Publishing Agreement
Keyword:
COHERENCE TOMOGRAPHY IMAGES
NOISE-REDUCTION
CATHETER
MICROANGIOGRAPHY
REGULARIZATION
ENDOSCOPE
RETINA
BIOPSY
CANCER
期刊
IF:
3.3
论文数:
6.1W
被引数:
14.3W
机构
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