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Spherical Nucleic Acids

delete2012-01-09
delete1.1K
PRE
AI
J
Joshua I. Cutler
E
Evelyn Auyeung
C
Chad A. Mirkin *
DOI:10.1021/ja209351udelete
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摘要

摘要

En 中文
A historical perspective of the development of spherical nucleic acid (SNA) conjugates and other three-dimensional nucleic acid nanostructures is provided. This Perspective details the synthetic methods for preparing them, followed by a discussion of their unique properties and theoretical and experimental models for understanding them. Important examples of technological advances made possible by their fundamental properties spanning the fields of chemistry, molecular diagnostics, gene regulation, medicine, and materials science are also presented.
Keyword:
MODIFIED GOLD-NANOPARTICLE
COLORIMETRIC DETECTION
ASYMMETRIC FUNCTIONALIZATION
STRUCTURAL-CHARACTERIZATION
SCAVENGER RECEPTORS
OPTICAL-PROPERTIES
PARTICLE-SIZE
DNA DETECTION
CAGED DIMERS
NANO-FLARES
AI总结

AI总结

对已上传原文的论文进行重点信息的提取,主要内容包括:简要概述、研究摘要、背景介绍、关键亮点、图文解析、展望与总结。

期刊

Journal of the American Chemical Society 封面图
Journal of the American Chemical Society
IF:
15.6
论文数:
20.0W
被引数:
60.2W

机构

N
Northwestern University
学者数:
6.2W
论文数: 5.3W
被引数: 3.9K
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