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Spontaneous regression of B-cell acute lymphoblastic leukemia with PAX5 alterations at relapse: a case report

delete2026-07-31
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V
Vadim Lesan *
J
Joerg Bittenbring
S
Sarah Altmeyer
DOI:10.1007/s00277-026-06825-4delete
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Abstract

Abstract

En 中文
Acute lymphoblastic leukemia is the most common pediatric hematological disease representing less than 1% of hematological diseases in adults. The prognosis of ALL improved significantly in the last decades. Almost all patients require a therapy at the time of diagnosis. Rare cases of spontaneous remission of ALL have been described. We report a case of B-ALL that underwent spontaneous remission after an episode of infection and describe the cytogenetic changes associated with this uncommon clinical presentation of B-ALL.
Keywords:
Spontaneous regression
B-ALL
PAX5 alterations
Case report

Journal

Annals of Hematology cover
Annals of Hematology
IF:
2.4
Papers:
8.3K
Citations:
8.1K

Organization

D
Department of Hematology and Oncology
Scholars:
359
Papers: 135
Citations: 1
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