SSN2V: unsupervised OCT denoising using speckle split

doi:10.1038/s41598-023-37324-5

2023-06-27

Julia Schottenhamml *

DOI：10.1038/s41598-023-37324-5

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摘要

En 中文

Denoising in optical coherence tomography (OCT) is important to compensate the low signal-to-noise ratio originating from laser speckle. In recent years learning algorithms have been established as the most powerful denoising approach. Especially unsupervised denoising is an interesting topic since it is not possible to acquire noise free scans with OCT. However, speckle in in-vivo OCT images contains not only noise but also information about blood flow. Existing OCT denoising algorithms treat all speckle equally and do not distinguish between the noise component and the flow information component of speckle. Consequently they either tend to either remove all speckle or denoise insufficiently. Unsupervised denoising methods tend to remove all speckle but create results that have a blurry impression which is not desired in a clinical application. To this end we propose the concept, that an OCT denoising method should, besides reducing uninformative noise, additionally preserve the flow-related speckle information. In this work, we present a fully unsupervised algorithm for single-frame OCT denoising (SSN2V) that fulfills these goals by incorporating known operators into our network. This additional constraint greatly improves the denoising capability compared to a network without. Quantitative and qualitative results show that the proposed method can effectively reduce the speckle noise in OCT B-scans of the human retina while maintaining a sharp impression outperforming the compared methods.

Keyword:

OPTICAL COHERENCE TOMOGRAPHY

NOISE SUPPRESSION

REDUCTION

IMAGES

FILTER

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期刊

Scientific Reports

IF:

3.9

论文数:

27.8W

被引数:

83.5W

机构

University of Erlangen Nuremberg

学者数:

3.2W

论文数: 2.6W

被引数: 29

引用论文

A Deep Learning Approach to Denoise Optical Coherence Tomography Images of the Optic Nerve Head

SCIENTIFIC REPORTS

IF3.9

2019-10-08

OAAI

Devalla, Sripad Krishna; Subramanian, Giridhar; Tan Hung Pham; Wang, Xiaofei; Perera, Shamira; Tun, Tin A.; Aung, Tin; Schmetterer, Leopold; Thiery, Alexandre H.; Girard, Michael J. A.

Short communication: Insect detection using a machine learning model

Nusantara Bioscience

IF0

2021-02-20