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Statistical error mapping for reliable quantitative T1 imaging
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DOI：10.1002/jmri.1880060143.png)
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We developed a statistically based error image for rapid appreciation of unreliable regions in quantitative water proton T1 images, The chi-squared error and coefficient of variation of the fitted parameter were used to estimate uncertainties in the goodness-of-fit to mono-exponential T1 relaxation and the reliability of the calculated T1, respectively, for each pixel, Errors exceeding a statistical threshold based on a .1 acceptance criterion were displayed as a color-coded overlay on the T1 image, Error maps of quantitative T1 images from 31 healthy volunteers showed a characteristic error structure; few pixels within the parenchyma had excessive errors. Clinical cases with stroke and sickle cell disease showed deviations from the normal pattern in the spatial distribution and magnitude of chi-squared errors, Disease states may deviate from monoexponential T1 relaxation more than normal brain does. The color-coded error map is a valuable tool for investigators using quantitative MR imaging to determine tissue relaxation parameters.
Keyword:
magnetic resonance (MR), image processing
magnetic resonance (MR), physics
magnetic resonance (MR), relaxometry
image, analysis
computers, diagnostic aid
期刊
IF:
3.5
论文数:
10.0K
被引数:
2.0W
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分享收藏TISSUE CHARACTERIZATION WITH T1, T2, AND PROTON DENSITY VALUES - RESULTS IN 160 PATIENTS WITH BRAIN-TUMORS.png)
RADIOLOGY
RADIOLOGYIF15.2
PREAI
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