Stem cell-based therapy for COVID-19

Xiaomei Chen

doi:10.1016/j.intimp.2023.110890

2023-11-01

DOI：10.1016/j.intimp.2023.110890

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摘要

En 中文

While The World Health Organization (WHO) has announced that COVID-19 is no longer a public health emergency of international concern(PHEIC), the risk of reinfection and new emerging variants still makes it crucial to study and work towards the prevention of COVID-19. Stem cell and stem cell-like derivatives have shown some promising results in clinical trials and preclinical studies as an alternative treatment option for the pulmonary illnesses caused by the COVID-19 and can be used as a potential vaccine. In this review, we will systematically summarize the pathophysiological process and potential mechanisms underlying stem cell-based therapy in COVID-19, and the registered COVID-19 clinical trials, and engineered extracellular vesicle as a potential vaccine for preventing COVID-19.

Keyword:

COVID-19

Mesenchymal stem cells

Extracellular vesicle

Cell -based therapy

Clinical trials

Vaccines

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期刊

International Immunopharmacology

IF:

4.7

论文数:

1.6W

被引数:

4.1W

机构

guangdong academy of medical sciences & guangdong general hospital

学者数:

7.4K

论文数: 4.6K

被引数: 8

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