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Stroop-test interference in bipolar disorder
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DOI：10.1192/bjp.bp.108.052639.png)
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We analysed Stroop (neuropsychological screening test) measures of response inhibition in 18 twin pairs discordant for bipolar I disorder compared with 17 healthy control pairs, as well as 40 singletons with bipolar disorder with psychotic features and a family history of psychosis, 46 of their first-degree relatives without bipolar disorder or psychosis and 48 controls. in both studies, individuals with bipolar disorder showed Stroop deficits and their first-degree relatives showed intact performance. lit the twin patients, an interference score was associated with depressive symptoms. Having a first-degree relative with bipolar disorder, ever a familial, psychotic form, did not confer risk for enhanced susceptibility to interference in our studies.
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