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Structure Elucidation of Leadbeaterin-1: the Main Fish-Killing Toxin from Chrysochromulina leadbeateri Blooms in Northern Norwegian Fjords

delete2026-03-10
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PRE
AI
X
Xinhui Wang
A
Anita Solhaug
B
Bruno C. Garrido
E
Elizabeth Mudge
M
Mathias Fon
A
Aaron J.C. Andersen
I
Ingunn A. Samdal
B
Bente Edvardsen
C
Charlotte H. Gotfredsen
P
Per Juel Hansen
C
Christopher O. Miles *
T
Thomas Ostenfeld Larsen *
DOI：10.1016/j.hal.2026.103104delete
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Abstract

Abstract

En 中文
• Purification, structure elucidation and quantitative NMR of leadbeaterin-1 • Structural similarity to karlotoxins supports ancestral link to haptophytes • Identification of glycolic acid esters as a leadbeaterin pro-toxins • Quantitative toxicity of leadbeaterin-1 in two gill cell assays • Cellular quota of leadbeaterins determined in three C. leadbeateri strains
Keywords:
Leadbeaterin-1
Chrysochromulina leadbeateri
toxin structure
gill cell assays
glycolic acid esters

Journal

Harmful Algae cover
Harmful Algae
IF:
4.5
Papers:
2.5K
Citations:
9.2K

Organization

N
Norwegian Veterinary Institute
Scholars:
953
Papers: 787
Citations: 803
U
University of Copenhagen
Scholars:
7.6W
Papers: 6.6W
Citations: 86
U
university of oslo
Scholars:
4.2W
Papers: 3.5W
Citations: 53
T
technical university of denmark
Scholars:
2.6W
Papers: 2.8W
Citations: 37
N
national research council of canada
Scholars:
205
Papers: 87
Citations: 0
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