.png){kind=icon}
返回
Subsolid Lung Nodule Classification: A CT Criterion for Improving Interobserver Agreement
.png){kind=icon}
PRE
AI
DOI：10.1148/radiol.2017170044.png)
.png){kind=icon}
原文求助.png){kind=icon}
分享.png){kind=icon}
收藏
摘要
En 中文
Purpose: To evaluate an objective computed tomographic (CT) criterion for distinguishing between part-solid (PS) and nonsolid (NS) lung nodules. Materials and Methods: This study received institutional review board approval, and patients gave informed consent. Preoperative CT studies in all patients who underwent surgery for subsolid nodules between 2008 and 2015 were first reviewed by two senior radiologists, who subjectively classified the nodules as PS or NS. A second reading performed 1 month later used predefined classification criteria and involved a third senior radiologist as well as three junior radiologists. Subsolid nodules were classified as PS if a solid portion was detectable in the mediastinal window setting (nonmeasurable, < 50%, or > 50% of the entire nodule) and were otherwise classified as NS (subclassified as pure or heterogeneous). Interreader agreement was assessed with kappa statistics and the intraclass correlation coefficient (ICC). Results: A total of 99 nodules measuring a median of 20 mm (range, 5-47 mm) in lung window CT images were analyzed. Senior radiologist agreement on the PS/NS distinction increased from moderate (kappa = 0.54; 95% confidence interval [CI]: 0.37, 0.71) to excellent (kappa = 0.89; 95% CI: 0.80, 0.98) between the first and second readings. At the second readings, agreement among senior and junior radiologists was excellent for PS/NS distinction (ICC = 0.87; 95% CI: 0.83, 0.90) and for subcategorization (ICC = 0.82; 95% CI: 0.77, 0.87). When a solid portion was measurable in the mediastinal window, the specificity for adenocarcinoma invasiveness ranged from 86% to 96%. Conclusion: Detection of a solid portion in the mediastinal window setting allows subsolid nodules to be classified as PS with excellent interreader agreement. If the solid portion is measurable, the specificity for adenocarcinoma invasiveness is high. (C) RSNA, 2017
Keyword:
GROUND-GLASS OPACITY
RESOLUTION COMPUTED-TOMOGRAPHY
THIN-SECTION CT
INVASIVE-PULMONARY-ADENOCARCINOMAS
SOLID COMPONENT SIZE
IASLC/ATS/ERS CLASSIFICATION
CANCER
DIFFERENTIATION
ASSOCIATION
VARIABILITY
AI总结
对已上传原文的论文进行重点信息的提取，主要内容包括：简要概述、研究摘要、背景介绍、关键亮点、图文解析、展望与总结。
期刊
IF:
15.2
论文数:
4.0W
被引数:
6.0W
机构
引用论文
Persistent Pure Ground-Glass Opacity Lung Nodules ≥ 10 mm in Diameter at CT Scan Histopathologic Comparisons and Prognostic Implications.png)
CHEST
CHESTIF8.6
PREAI
分享收藏Evaluation of Individuals With Pulmonary Nodules: When Is It Lung Cancer? Diagnosis and Management of Lung Cancer, 3rd ed: American College of Chest Physicians Evidence-Based Clinical Practice GuidelinesCHEST
OAAI
CHESTIF8.6
OAAI分享收藏
查看更多内容