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Super-resolution head and neck MRA using deep machine learning
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DOI：10.1002/mrm.28738.png)
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摘要
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Purpose: To probe the feasibility of deep learning-based super-resolution (SR) reconstruction applied to nonenhanced MR angiography (MRA) of the head and neck. Methods: High-resolution 3D thin-slab stack-of-stars quiescent interval slice-selective (QISS) MRA of the head and neck was obtained in eight subjects (seven healthy volunteers, one patient) at 3T. The spatial resolution of high-resolution ground-truth MRA data in the slice-encoding direction was reduced by factors of 2 to 6. Four deep neural network (DNN) SR reconstructions were applied, with two based on U-Net architectures (2D and 3D) and two (2D and 3D) consisting of serial convolutions with a residual connection. SR images were compared to ground-truth high-resolution data using Dice similarity coefficient (DSC), structural similarity index measure (SSIM), arterial diameter, and arterial sharpness measurements. Image review of the optimal DNN SR reconstruction was done by two experienced neuroradiologists. Results: DNN SR of up to twofold and fourfold lower-resolution (LR) input volumes provided images that resembled those of the original high-resolution ground-truth volumes for intracranial and extracranial arterial segments, and improved DSC, SSIM, arterial diameters, and arterial sharpness relative to LR volumes (P<.001). The 3D DNN SR outperformed 2D DNN SR reconstruction. According to two neuroradiologists, 3D DNN SR reconstruction consistently improved image quality with respect to LR input volumes (P<.001). Conclusion: DNN-based SR reconstruction of 3D head and neck QISS MRA offers the potential for up to fourfold reduction in acquisition time for neck vessels without the need to commensurately sacrifice spatial resolution.
Keyword:
deep learning
head
MRA
neck
super-resolution
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