.png){kind=icon}
返回
Super-resolution microscopy to decipher multi-molecular assemblies
.png){kind=icon}
OA
AI
DOI：10.1016/j.sbi.2018.03.017.png)
.png){kind=icon}
.png){kind=icon}
分享.png){kind=icon}
收藏
摘要
En 中文
Super-resolution fluorescence microscopy (SRM) is increasingly being applied as a complementary method to resolve the organization of large biomolecular assemblies. One of its main advantages is that it provides information on protein organization and identity simultaneously, within the native cellular milieu. It also extends the accessible range of structures up to the micrometer scale, offering complementary information relative to classical structural biology methods. Furthermore, SRM is capable of resolving the organization of some biomolecular assemblies not accessible to other methods. We highlight these advantages within the context of deciphering the structure of the centrosome and chromatin, and discuss how computational data post-processing has been adapted for SRM data. We also outline current limitations and potential approaches to overcome them.
Keyword:
NUCLEAR-PORE COMPLEX
LIVE-CELL
REVEALS
RESOLUTION
FLUORESCENCE
ARCHITECTURE
PROTEINS
SHELTERIN
NANOSCOPY
LIGHT
AI总结
对已上传原文的论文进行重点信息的提取，主要内容包括：简要概述、研究摘要、背景介绍、关键亮点、图文解析、展望与总结。
期刊
IF:
7
论文数:
3.8K
被引数:
1.3W
机构
引用论文
STED Nanoscopy Reveals the Ubiquity of Subcortical Cytoskeleton Periodicity in Living Neurons.png)
CELL REPORTSOAAI
CELL REPORTSIF6.9
OAAI分享收藏VirusMapper: open-source nanoscale mapping of viral architecture through super-resolution microscopySCIENTIFIC REPORTSOAAI
SCIENTIFIC REPORTSIF3.9
OAAI分享收藏
查看更多内容