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Surface Engineering and Patterning Using Parylene for Biological Applications
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DOI：10.3390/ma3031803.png)
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摘要
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Parylene is a family of chemically vapour deposited polymer with material properties that are attractive for biomedicine and nanobiotechnology. Chemically inert parylene peel-off stencils have been demonstrated for micropatterning biomolecular arrays with high uniformity, precise spatial control down to nanoscale resolution. Such micropatterned surfaces are beneficial in engineering biosensors and biological microenvironments. A variety of substituted precursors enables direct coating of functionalised parylenes onto biomedical implants and microfluidics, providing a convenient method for designing biocompatible and bioactive surfaces. This article will review the emerging role and applications of parylene as a biomaterial for surface chemical modification and provide a future outlook.
Keyword:
parylene
micropatterning
surface modification
[2.2]paracyclophane
biomaterial
bioactive
biomolecular
nanobiotechnology
microarray
microfluidic
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3.2
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5.7W
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15.1W
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