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Surface functional DNA density control by programmable molecular defects
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DOI：10.1039/c7cc09908h.png)
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摘要
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Programmable surface-patterned functional DNA density is achieved via manipulation of molecular-level defects through chemical lift-off lithography. Artificial SAM defects are well-tunable by a contact-induced reaction, enabling molecular environment guidance and DNA insertion to be spatially and quantitatively addressable. This straightforward molecular density control creates an advanced avenue toward fabricating multiplexed bioactive substrates.
Keyword:
SELF-ASSEMBLED MONOLAYERS
DIP-PEN NANOLITHOGRAPHY
SINGLE-STRANDED-DNA
DIRECTED IMMOBILIZATION
GOLD
PROBE
OLIGONUCLEOTIDE
LITHOGRAPHY
ADSORPTION
INTERFACE
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4.2
论文数:
5.9W
被引数:
16.5W
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