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Synergistic toxicity of T-2 toxin and diniconazole in zebrafish: Involvement of gut-liver homeostasis dysregulation and ferroptosis
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DOI：10.1016/j.ecoenv.2026.120638.png)
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Abstract
En 中文
• T-2 and DIN exhibit synergistic acute toxicity in zebrafish. • T-2 and DIN disrupt gut microbiota and gut-liver homeostasis. • Intestinal and hepatic LPS levels correlate positively after T-2 and DIN exposure. • Oxidative stress-ferroptosis cascade contributes to hepatic toxicity. • Zebrafish exhibit sex-specific toxic responses to T-2 and DIN exposure.
Keywords:
T-2 Toxin
Diniconazole
Ferroptosis
Gut Microbiota
Hepatotoxicity
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