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Systemic sclerosis. A disease with multiple faces

delete2025-12-01
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OA
AI
C
Caroline Evers
J
Jörg Distler
DOI：10.1007/s00108-025-02024-xdelete
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摘要

摘要

En 中文
系统性硬化症（SSc）是一种在风湿病谱系中较为罕见的自身免疫性结缔组织疾病。其特点为血管病变和炎症性纤维化共同作用，影响皮肤及多种内部器官。该病表现异质性显著，可能增加诊断难度，因此在监测和治疗过程中必须予以充分考虑。近年来，研究进展扩大了SSc可用的治疗选择范围。治疗策略需根据每位患者的具体临床表现进行个体化调整。本文旨在概述SSc的多样化疾病表现及当前的治疗方法。为优化患者护理，风湿科医生、呼吸科医生、消化科医生、心内科医生、肾内科医生及全科医生之间的密切协作至关重要。
Keyword:
Skin fibrosis
Raynaud disease
Connective tissue diseases
Immunosuppression therapy
Antifibrotic therapy
Skin fibrosis
Raynaud disease
Connective tissue diseases
Immunosuppression therapy
Antifibrotic therapy
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期刊

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INNERE MEDIZIN
IF:
0.6
论文数:
368
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机构

U
university zurich hospital
学者数:
1.2W
论文数: 9.5K
被引数: 7
U
university of zurich
学者数:
5.1W
论文数: 4.0W
被引数: 65
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