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Targeted Therapy Evolution from Defining a Sub-population to Crossing Multi-indications
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DOI：10.34172/apb.43306.png)
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Abstract
En 中文
Purpose: It tends not only to shed lights on an emerging classification framework of disease according to the shared molecular pathogenesis across various organs/tissues, but also to inspire more efficient paradigms of pharmaceutic innovation in a broader medical perspective. Methods: Literature review and re-thinking. Results: This article has sorted out an updated profile of the outstanding targeted medications with an extending list of clinical indications in oncology and beyond. Conclusion: Pharmaceutic development can be processed in a less risky and more affordable manner through drug repurpose or tissue agnostic approval.
Keywords:
Targeted therapy
Drug repurpose
Tissue agnostic approval
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