.png){kind=icon}
返回
Tau Structures
.png){kind=icon}
OA
AI
DOI：10.3389/fnagi.2016.00262.png)
.png){kind=icon}
.png){kind=icon}
分享.png){kind=icon}
收藏
摘要
En 中文
Tau is a microtubule-associated protein that plays an important role in axonal stabilization, neuronal development, and neuronal polarity. In this review, we focus on the primary, secondary, tertiary, and quaternary tau structures. We describe the structure of tau from its specific residues until its conformation in dimers, oligomers, and larger polymers in physiological and pathological situations.
Keyword:
motifs
tau residues
posttranslational modifications
PHFs
tubuling binding
aggregation
microtubule-associated proteins
AI总结
对已上传原文的论文进行重点信息的提取，主要内容包括：简要概述、研究摘要、背景介绍、关键亮点、图文解析、展望与总结。
期刊
IF:
4.5
论文数:
8.4K
被引数:
3.5W
机构
引用论文
分享收藏Hyperphosphorylation determines both the spread and the morphology of tau pathology.png)
ALZHEIMERS & DEMENTIA
ALZHEIMERS & DEMENTIAIF11.1
PREAI
分享收藏Spatiotemporal variation of soil moisture in Northern China based on climate change initiative data
PREAI
分享收藏Cleavage of tau by asparagine endopeptidase mediates the neurofibrillary pathology in Alzheimer's diseaseNATURE MEDICINEOAAI
NATURE MEDICINEIF50
OAAI分享收藏
查看更多内容