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Testing likelihood ratios produced from complex DNA profiles
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DOI：10.1016/j.fsigen.2015.01.008.png)
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The performance of any model used to analyse DNA profile evidence should be tested using simulation, large scale validation studies based on ground-truth cases, or alignment with trends predicted by theory. We investigate a number of diagnostics to assess the performance of the model using H-d true tests. Of particular focus in this work is the proportion of comparisons to non-contributors that yield a likelihood ratio (LR) higher than or equal to the likelihood ratio of a known contributor (LRPOI), designated as p, and the average LR for Hd true tests. Theory predicts that p should always be less than or equal to 1/LRPOI and hence the observation of this in any particular case is of limited use. A better diagnostic is the average LR for H-d true which should be near to 1. We test the performance of a continuous interpretation model on nine DNA profiles of varying quality and complexity and verify the theoretical expectations. (c) 2015 Elsevier Ireland Ltd. All rights reserved.
Keyword:
DNA profile interpretation
Mixtures
Likelihood ratios
Performance tests
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