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The added value of 3.0 T quantitative multivoxel proton 1H-MR spectroscopy in the diagnostic work-up of breast lesions
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DOI:10.1016/j.ejrad.2026.113040.png)
Abstract
En 中文
• Important to reduce ultrasound examinations and biopsies in benign breast lesions. • Multivoxel 3.0T1H-MRS (lesions ≥ 1 cm) resulted in a high NPV of 89%. • Most malignancies can be ruled out based on choline values < 1.70 mmol/L.
Keywords:
Breast
Breast cancer
Magnetic resonance imaging
Magnetic resonance spectroscopy
Spectroscopy
AUC
Area under the curve
Cho
Choline
Cr
Creatine
CSI
Chemical shift imaging
DCE-T1
Dynamic contrast enhanced T1-weigted imaging
DCIS
Ductal carcinoma in situ
ER
Estrogen receptor
HER2
Human epidermal growth factor receptor 2
mmol/L
Millimole per liter
MRS
Proton 1H-magnetic resonance spectroscopy
NPV
Negative predictive value
NST
No special type
PR
progesterone receptor
SNR
Signal-to-noise-ratio
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