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The Impact of Nutrition, Exercise, and Pharmacotherapy on Menstrual Health in Adolescents with Overweight and Obesity
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DOI：10.1016/j.nut.2025.113021.png)
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Abstract
En 中文
• Expanded the discussion of foundational studies on HPG axis regulation and metabolic influences on puberty. • Added a summary figure illustrating the HPG axis and key hormonal interactions (leptin, insulin, ghrelin), as well as a table summarizing major metabolic parameters and their effects on puberty. • Enhanced the sections on nutritional and physical activity interventions, including discussion of dietary patterns and comparisons between resistance and aerobic exercise in relation to PCOS outcomes. • Broadened the “Prevention, Screening, and Lifestyle Interventions” section to include implications for school-based education and public health policy. • Clarified terminology, standardized abbreviations, and provided BMI thresholds and diagnostic clarifications consistent with current international guidelines for PCOS diagnosis in adolescents. • Expanded our discussion of GLP-1 receptor agonists to reflect caution regarding their limited data in adolescents, while referencing recent adult studies and considering translation to younger populations. • Included key citations and ensured consistency of terminology throughout.
Journal
IF:
3.8
Papers:
1.2W
Citations:
3.7W
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