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The Significance of Non-T-Cell Pathways in Graft Rejection: Implications for Transplant Tolerance
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DOI：10.1097/TP.0b013e3181efcfe9.png)
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Abstract
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Both innate and adaptive immune cells are actively involved in the initiation and destruction of allotransplants, and there is a true need now to look beyond T cells in the allograft response, examining various non-T-cell types in transplant models and how such cell types interact with T cells in determining the fate of an allograft. Studies in this area may lead to further improvement in transplant outcomes.
Keywords:
Innate immunity
NK cells
Dendritic cells
Tolerance
Transplantation
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