The Transporter Classification Database (TCDB): recent advances

Milton H. Saier

doi:10.1093/nar/gkv1103

2015-11-05

570

Gabriel Moreno‐Hagelsieb

DOI：10.1093/nar/gkv1103

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摘要

En 中文

The Transporter Classification Database (TCDB; http://www.tcdb.org) is a freely accessible reference database for transport protein research, which provides structural, functional, mechanistic, evolutionary and disease/medical information about transporters from organisms of all types. TCDB is the only transport protein classification database adopted by the International Union of Biochemistry and Molecular Biology (IUBMB). It consists of more than 10 000 non-redundant transport systems with more than 11 000 reference citations, classified into over 1000 transporter families. Transporters in TCDB can be single or multi-component systems, categorized in a functional/phylogenetic hierarchical system of classes, subclasses, families, subfamilies and transport systems. TCDB also includes updated software designed to analyze the distinctive features of transport proteins, extending its usefulness. Here we present a comprehensive update of the database contents and features and summarize recent discoveries recorded in TCDB.

Keyword:

WEB-BASED PROGRAM

BIOINFORMATIC ANALYSES

PHYLOGENETIC CHARACTERIZATION

ABC TRANSPORTERS

PROTEINS

TOPOLOGY

SUPERFAMILY

PREDICTION

SEQUENCE

FAMILY

AI总结

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期刊

Nucleic Acids Research

IF:

13.1

论文数:

3.6W

被引数:

29.0W

机构

boston university

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3.8W

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University of California System

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