The usual suspects

doi:10.1016/j.anai.2025.04.013

2025-04-25

PRE

DOI：10.1016/j.anai.2025.04.013

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反复喘息和哮喘是主要的健康问题，尤其是在儿童中。呼吸道病毒感染已知可诱发反复喘息和哮喘。与大多数反复喘息和哮喘发展相关的两种呼吸道病毒是呼吸道合胞病毒（RSV）和鼻病毒（RV）。本综述评估了这两种病毒在喘息和哮喘发展中所起的作用。RSV倾向于驱动那些在生命最初2至6个月内患有严重感染且无先前特应性体质的婴儿发生反复喘息。这与RV形成对比，后者倾向于驱动那些具有先前特应性体质者发生喘息和哮喘。在综述中，探讨了已被提出以驱动哮喘和喘息发展的机制。最后，讨论了疫苗等新进展。特别是，RSV疫苗和治疗有潜力改变反复喘息的发展，尽管RV的疫苗和治疗仍不明确。RSV和RV仍然是幼儿反复喘息的主要来源。

Keyword:

RSV

rhinovirus

asthma

wheeze

childhood respiratory infections

期刊

Annals of Allergy Asthma and Immunology

IF:

4.7

论文数:

281

被引数:

1.0W

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the ohio state university college of medicine

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200

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cleveland clinic akron general

学者数:

论文数: 14

被引数: 0

The Ohio State University Wexner Medical Center and Nationwide Children's Hospital

学者数:

论文数: 1

被引数: 0

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