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ThymUS approaching maturity
DOI:10.1038/s41590-025-02296-3.png)
摘要
En 中文
胸腺产生T细胞,对胸腺生物学的深入理解可能具有治疗潜力。本文总结了2025年ThymUS会议,重点关注基础见解和转化潜力。
Keyword:
thymus
T cells
thymus biology
translational potential
ThymUS conference
期刊
IF:
27.6
论文数:
6.4K
被引数:
5.6W
机构
引用论文
A RORγt+ cell instructs gut microbiota-specific Treg cell differentiationRor γ t细胞指导肠道菌群特异性Treg细胞分化
Nature
IF0
Single-cell multiomics defines tolerogenic extrathymic Aire-expressing populations with unique homology to thymic epithelium单细胞多组学定义了与胸腺上皮具有独特同源性的致耐受性胸腺外Aire表达群体
SCIENCE IMMUNOLOGY
IF16.3
LAMP2 regulates autophagy in the thymic epithelium and thymic stroma-dependent CD4 T cell development
AUTOPHAGY
IF14.3
Novel antigen-presenting cell imparts Treg-dependent tolerance to gut microbiota新型抗原呈递细胞赋予Treg依赖性对肠道菌群的耐受性
Nature
IF0
Thymic epithelial cells co-opt lineage-defining transcription factors to eliminate autoreactive T cells胸腺上皮细胞共选择谱系定义转录因子以消除自身反应性T细胞
Cell
IF0
Coreceptor reversal in the thymus:: Signaled CD4+8+ thymocytes initially terminate CD8 transcription even when differentiating into CD8+ T cells
IMMUNITY
IF26.3
DLL4 and VCAM1 enhance the emergence of T cell-competent hematopoietic progenitors from human pluripotent stem cells
SCIENCE ADVANCES
IF12.5
Foxn1 regulates key target genes essential for T cell development in postnatal thymic epithelial cells
NATURE IMMUNOLOGY
IF27.6

