.png){kind=icon}
返回
Thyroid dysfunction in COVID-19 patients
.png){kind=icon}
OA
AI
DOI：10.1007/s40618-021-01599-0.png)
.png){kind=icon}
.png){kind=icon}
分享.png){kind=icon}
收藏
摘要
En 中文
Purpose Non thyroidal illness syndrome (NTIS) or euthyroid sick syndrome (ESS) is a possible biochemical finding in euthyroid patients with severe diseases. It is characterized by a reduction of serum T-3 (fT3), sometimes followed by reduction of serum T-4 (fT4). The relationship between thyroid hormones levels and mortality is well known and different studies showed a direct association between NTIS and mortality. The sudden spread of the 2019 novel coronavirus (SARS-CoV 2) infection (COVID-19) and its high mortality become a world healthcare problem. Our aim in this paper was to investigate if patients affected by COVID-19 presented NTIS and the relationship between thyroid function and severity of this infection. Methods We evaluated the thyroid function in two different groups of consecutive patients affected by COVID-19 with respect to a control group of euthyroid patients. Group A included patients hospitalized for COVID-19 pneumonia while patients requiring intensive care unit (ICU) for acute respiratory syndrome formed the group B. Group C identified the control group of euthyroid patients. Results Patients from group A and group B showed a statistically significant reduction in fT3 and TSH compared to group C. In group B, compared to group A, a further statistically significant reduction of fT3 and TSH was found. Conclusions COVID-19 in-patients can present NTIS. FT3 and TSH serum levels are lower in patients with more severe symptoms.
Keyword:
Thyroid function
Thyroid hormones
COVID-19
SARS-CoV 2
Non-thyroidal illness syndrome
Euthyroid sick syndrome
AI总结
对已上传原文的论文进行重点信息的提取，主要内容包括：简要概述、研究摘要、背景介绍、关键亮点、图文解析、展望与总结。
期刊
J
IF:
3.5
论文数:
6.1K
被引数:
8.9K
机构
引用论文
Detection of 2019 novel coronavirus (2019-nCoV) by real-time RT-PCR (Publication with Expression of Concern)通过实时rt-pcr检测2019新型冠状病毒(2019-nCoV) (表达关注的出版物).png)
EUROSURVEILLANCEOAAI
EUROSURVEILLANCEIF7.8
OAAI分享收藏
查看更多内容