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TICT-based thiophene donor-π-acceptor fluorescent sensors for selective detection of tau and amyloid-β aggregates in cellular and brain tissues
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DOI：10.1016/j.snb.2026.140632.png)
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Abstract
En 中文
• TICT-based fluorescent probes were developed for selective detection of tau and Aβ aggregates. • Solvatochromism, Lippert–Mataga, viscosity, and DFT calculations confirmed the TICT photophysical behavior of the probes. • Probe 4a and 5d selectively detected tau and Aβ aggregates, respectively, in living cells. • Probe 5d selectively labeled Aβ plaques in mouse brain tissues with high specificity.
Journal
IF:
7.7
Papers:
3.3W
Citations:
12.6W
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Cited Papers