Tissue-electronics interfaces: from implantable devices to engineered tissues

doi:10.1038/natrevmats.2017.76

2017-11-28

413

PRE

Ron Feiner

Tal Dvir *

DOI：10.1038/natrevmats.2017.76

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摘要

En 中文

Biomedical electronic devices are interfaced with the human body to extract precise medical data and to interfere with tissue function by providing electrical stimuli. In this Review, we outline physiologically and pathologically relevant tissue properties and processes that are important for designing implantable electronic devices. We summarize design principles for flexible and stretchable electronics that adapt to the mechanics of soft tissues, such as those including conducting polymers, liquid metal alloys, metallic buckling and meandering architectures. We further discuss technologies for inserting devices into the body in a minimally invasive manner and for eliminating them without further intervention. Finally, we introduce the concept of integrating electronic devices with biomaterials and cells, and we envision how such technologies may lead to the development of bionic organs for regenerative medicine.

Keyword:

ON-A-CHIP

POLY(ETHER URETHANE) BIODEGRADATION

SYRINGE-INJECTABLE ELECTRONICS

DRUG-DELIVERY

POLY(CARBONATE URETHANE)

TRANSIENT ELECTRONICS

POLYMER DEGRADATION

IN-VITRO

SILICON

SENSORS

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期刊

Nature Reviews Materials

IF:

86.2

论文数:

1.2K

被引数:

4.3W

机构

Tel Aviv University

学者数:

3.7W

论文数: 3.0W

被引数: 3.6W

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