logo
科言猫学术研究的AI总结
language
手机端手机端
  • Phone Feature微信小程序
简体中文简体中文
notice消息通知
博客博客
delete
arrow
返回

TNFα in synaptic function: switching gears

delete2012-10-01
delete221
PRE
AI
M
Mirko Santello
A
Andrea Volterra *
DOI：10.1016/j.tins.2012.06.001delete
delete原文链接
delete原文求助
delete分享
delete收藏
摘要

摘要

En 中文
已知病理性脑状态诱导大量产生促炎细胞因子，包括肿瘤坏死因子 α (TNF α)。在低得多的水平下，这些细胞因子也存在于健康的大脑中，在那里人们越来越认识到它们发挥调节作用。最近的研究表明，TNF α 在控制突触传递和可塑性方面起着重要作用。在这里，我们讨论了支持TNF α 调节突触的证据和潜在的细胞机制，包括控制AMPA受体运输和星形胶质细胞释放谷氨酸。这些发现表明，TNF α 水平的升高 (由神经系统感染，损伤或疾病引起) 将细胞因子的生理作用转化为有害作用。这种功能转换可能会导致几种脑部疾病的认知改变。
Keyword:
cytokines
TNF alpha
synaptic transmission
glia
gliotransmission
inflammation
AI总结

AI总结

对已上传原文的论文进行重点信息的提取，主要内容包括：简要概述、研究摘要、背景介绍、关键亮点、图文解析、展望与总结。

期刊

Trends in Neurosciences 封面图
Trends in Neurosciences
IF:
15.1
论文数:
5.3K
被引数:
2.2W

机构

U
University of Lausanne
学者数:
2.5W
论文数: 2.0W
被引数: 3.0W
引用论文

引用论文

A Tensor Based Deep Learning Technique for Intelligent Packet Routing
errGLOBECOM 2017 - 2017 IEEE Global Communications Conference
IF0
err2017-12-01
err0
PREAI
errBomin Mao; Zubair Md. Fadlullah; Fengxiao Tang; Nei Kato; Osamu Akashi; Takeru Inoue; Kimihiro Mizutani
err分享
err收藏
Spectral analysis for base composition of DNA undergoing melting
errJournal of Biochemical and Biophysical Methods
IF0
err1985-11-01
err0
PREAI
errR.D. Blake; Thomas G. Hydorn
err分享
err收藏
Strategy for Differentiating Autoimmune Pancreatitis From Pancreatic Cancer
errPancreas
IF0
err2008-10-01
err0
errOAAI
errTerumi Kamisawa; Mitsuho Imai; Pong Yui Chen; Yuyang Tu; Naoto Egawa; Kouji Tsuruta; Atsutake Okamoto; Mizuka Suzuki; Noriko Kamata
err分享
err收藏
On the formation of liquid crystalline texture in epoxy resins
errMacromolecular Symposia
IF0
err2011-03-04
err0
PREAI
errJanusz S. Grebowicz
err分享
err收藏
Divergent roles for p55 and p75 tumor necrosis factor receptors in the pathogenesis of MOG35-55-induced experimental autoimmune encephalomyelitis
errCELLULAR IMMUNOLOGY
IF2.9
err2000-10-01
err146
PREAI
errSuvannavejh, GC; Lee, HO; Padilla, J; Dal Canto, MC; Barrett, TA; Miller, SD
err分享
err收藏
Spontaneous Corneal Dystrophy and Generalized Basement Membrane Changes in Fischer-344 Rats
errToxicologic Pathology
IF0
err1992-05-01
err0
errOAAI
errRichard H. Bruner; Waldo F. Keller; Katherine A. Stitzel; Leonard J. Sauers; Paul J. Reer; Philip H. Long; Robert D. Bruce; Carl L. Alden
err分享
err收藏
Measurement of the incorporation of radioactive amino acids into protein by a filter-paper disk method
errArchives of Biochemistry and Biophysics
IF0
err1961-07-01
err0
PREAI
errRusty J. Mans; G.David Novelli
err分享
err收藏
Deformation of globular polysoaps: extension, confinement and extensional flow
errThe European Physical Journal B
IF0
err1999-05-01
err0
PREAI
errO.V. Borisov; A. Halperin
err分享
err收藏
Mitochondrial Deafness
errEar & Hearing
IF0
err2003-08-01
err0
PREAI
errNathan Fischel-Ghodsian
err分享
err收藏
Genetic deletion of TNF receptor suppresses excitatory synaptic transmission via reducing AMPA receptor synaptic localization in cortical neurons
errFASEB JOURNAL
IF4.2
err2011-10-07
err86
errOAAI
errHe, Ping; Liu, Qiang; Wu, Jie; Shen, Yong
err分享
err收藏
学者 查看更多内容