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Tourettic OCD: Same Same but Different?

delete2025-12-29
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Susanna Chang *
DOI：10.1007/s40474-025-00344-zdelete
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摘要

摘要

En 中文
综述目的：自首次引入Tourettic OCD (TOCD)这一术语以来，越来越多的研究探讨了妥瑞综合征(TS)等慢性抽动障碍与强迫症(OCD)之间重叠的方式以及它们如何保持区别。本简要综述旨在阐述现象学和神经生物学方面的发现，以及这些结果对TOCD评估和治疗的意义。 近期研究进展：临床上，除了发病年龄较早和男性占优势外，TOCD的典型特征是复杂的重复行为，这些行为融合了抽动特有的预感性感觉和OCD中常见的“恰到好处”的焦虑驱动力。神经生物学上，TOCD可能源于皮层-纹状体-丘脑-皮层(CSTC)通路的功能障碍，神经影像学表明其通路参与情况与单独的TS和OCD相比具有独特性但存在重叠，这为TOCD作为一种独特实体提供了依据。当前的评估建议强调灵活整合针对TS和OCD的成熟循证工具，并纳入评估感觉现象范围和目的的新方法。类似地，TOCD的干预措施受益于抽动和OCD行为及药物疗法的结合，目标是在个体化方式下灵活调整技术。 总结：综合来看，当前研究显示对TOCD作为具有独特临床特征和神经生物学的独立障碍的认识日益加深。最优评估和治疗策略仍在发展中，目前的建议具有多模态性质。未来研究方向指向制定正式诊断标准，以及为TOCD建立具体且定制化的评估和治疗方案。
Keyword:
Tourettic OCD
Obsessive compulsive disorder
Tic disorders
Comorbidity
Diagnosis
Treatment
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期刊

C
Current Developmental Disorders Reports
IF:
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论文数:
20
被引数:
839

机构

University of California System 封面图
University of California System
学者数:
37.5W
论文数: 33.7W
被引数: 6.6K
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