Translating the telomeres

doi:10.1016/j.tig.2023.04.009

2023-08-01

Mariarosaria De Rosa

Patricia L. Opresko *

DOI：10.1016/j.tig.2023.04.009

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摘要

En 中文

Telomeres are transcribed into long noncoding telomeric repeat-containing RNA (TERRA). Or so we thought. Recently, Al-Turki and Griffith provided evidence that TERRA can code for valine-arginine (VR) or glycine-leucine (GL) dipeptide repeat proteins by undergoing repeat-associated non-ATG (RAN) translation. This finding uncovers a new mechanism by which telomeres can impact cellular function.

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Trends in Genetics

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16.3

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3.4K

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机构

pennsylvania commonwealth system of higher education (pcshe)

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被引数: 177

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