.png){kind=icon}
.png){kind=icon}
Return
Tumor-infiltrating plasma cell profiling after PD-1 blockade reveals tumor-specific antibodies
.png){kind=icon}
OA
AI
R
A
J
C
L
D
K
J
G
L
V
R
N
T
C
A
E
C
K
S
DOI：10.1016/j.ccell.2026.07.001.png)
.png){kind=icon}
.png){kind=icon}
Share.png){kind=icon}
Save
Abstract
En 中文
• PD-1 blockade is associated with tumor-specific antibody development • Single-cell BCR mining identifies tumor-selective antibody lineages • Tumor antibodies bind citrullinated antigens on cancer- and tumor-promoting myeloid cells • PC-1 CAR T cells target tumors and tumor-promoting myeloid cells without off-tumor toxicity
Keywords:
tumor-reactive B cells
tumor antigens
tumor-infiltrating B cells
plasma cells in NSCLC
chimeric antigen receptor T cells
tumor-suppressive myeloid cells
tumor antibodies
tumor-reactive antibodies
citrullinated vimentin
AI Summary
Key information extracted from the uploaded paper, including a brief overview, abstract, background, key highlights, visual analysis, and future outlook.
Journal
IF:
44.5
Papers:
413
Citations:
5.6W
Organization
No organization information available
Cited Papers