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Tumor necrosis factor receptor-associated factor 6 (TRAF6) regulates Aeromonas hydrophila-induced autophagy in yellow catfish (Pelteobagrus fulvidraco)

delete2025-12-11
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PRE
AI
Z
Zhi-Wei Nie
Y
Yuan Hu
Y
Yun-Fei Dang *
J
Jiong Chen *
DOI：10.1016/j.fsi.2025.111066delete
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Abstract

Abstract

En 中文
• PfTRAF6 was identified and characterized from yellow catfish. • PfTRAF6 expression was upregulated after Aeromonas hydrophila infection. • PfTRAF6 knockdown reduced LC3-II formation and P62 phosphorylation. • PfTRAF6 regulated autophagosome formation in monocytes/macrophages. • PfTRAF6 plays a key role in bacterial infection–induced autophagy in fish.

Journal

F
Fish and Shellfish Immunology
IF:
3.9
Papers:
1.1W
Citations:
3.1W

Organization

N
Ningbo University
Scholars:
2.6W
Papers: 1.8W
Citations: 2.4W
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