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Two Patterns of Sacroiliac Joint Bone Marrow Oedema are apparent in AxSpA Determined by HLA-B27 Status, Body Mass Index or Psoriasis

delete2026-05-26
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OA
AI
K
Kerem Abacar
A
Andrea Di Matteo
G
Gabriele De Marco
K
Katya Meridor
J
Jake Weddell
S
Stephanie R Harrison
J
Jane Freeston
C
Claire Vandevelde
A
Andrew Barr
H
Harun Gupta
K
Kulveer Mankia
H
Helena Marzo-Ortega
D
Dennis McGonagle *
DOI:10.1016/j.jbspin.2026.106079delete
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Abstract

Abstract

En 中文
• Sacroiliac MRI reveals two predominant bone marrow oedema distribution patterns in axSpA • Upper SIJ oedema is associated with higher BMI and psoriasis, independent of HLA-B27 • Lower SIJ oedema aligns with classical HLA-B27–positive axial spondyloarthritis features • Upper SIJ oedema regresses with biologic therapy, supporting an inflammatory origin • Regional SIJ patterns reflect a biomechanical–immunological continuum in axSpA
Keywords:
axial spondyloarthritis
bone marrow oedema
sacroiliac joints
magnetic resonance imaging
psoriasis
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Joint Bone Spine cover
Joint Bone Spine
IF:
4.3
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4.2K
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L
leeds teaching hospitals nhs trust
Scholars:
200
Papers: 112
Citations: 2
U
university of leeds
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Citations: 45
L
leeds teaching hospitals trust
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Papers: 18
Citations: 0
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