.png){kind=icon}
返回
Understanding Cervical Cancer through Proteomics
.png){kind=icon}
OA
AI
DOI：10.3390/cells10081854.png)
.png){kind=icon}
.png){kind=icon}
分享.png){kind=icon}
收藏
摘要
En 中文
Cancer is one of the leading public health issues worldwide, and the number of cancer patients increases every day. Particularly, cervical cancer (CC) is still the second leading cause of cancer death in women from developing countries. Thus, it is essential to deepen our knowledge about the molecular pathogenesis of CC and propose new therapeutic targets and new methods to diagnose this disease in its early stages. Differential expression analysis using high-throughput techniques applied to biological samples allows determining the physiological state of normal cells and the changes produced by cancer development. The cluster of differential molecular profiles in the genome, the transcriptome, or the proteome is analyzed in the disease, and it is called the molecular signature of cancer. Proteomic analysis of biological samples of patients with different grades of cervical intraepithelial neoplasia (CIN) and CC has served to elucidate the pathways involved in the development and progression of cancer and identify cervical proteins associated with CC. However, several cervical carcinogenesis mechanisms are still unclear. Detecting pathologies in their earliest stages can significantly improve a patient's survival rate, prognosis, and recurrence. The present review is an update on the proteomic study of CC.
Keyword:
proteomic
cervical cancer
biomarkers
gene differential expression
AI总结
对已上传原文的论文进行重点信息的提取，主要内容包括：简要概述、研究摘要、背景介绍、关键亮点、图文解析、展望与总结。
期刊
IF:
5.2
论文数:
2.1W
被引数:
9.4W
机构
引用论文
Evaluation of an Automated Endotracheal Tube Cuff Controller During Simulated Mechanical VentilationOAAI
OAAI分享收藏Home Monitoring With a Modified Automatic Sphygmomanometer to Detect Recurrent Atrial Fibrillation
PREAI
分享收藏Multilevel omics for the discovery of biomarkers and therapeutic targets for stroke.png)
NATURE REVIEWS NEUROLOGY
NATURE REVIEWS NEUROLOGYIF33.1
PREAI
分享收藏
Laser-assisted rapid evaporative ionisation mass spectrometry (LA-REIMS) as a metabolomics platform in cervical cancer screening激光辅助快速蒸发电离质谱 (la-reims) 作为宫颈癌筛查的代谢组学平台EBIOMEDICINEOAAI
EBIOMEDICINEIF10.8
OAAI分享收藏
查看更多内容