.png){kind=icon}
返回
Understanding Clostridium difficile Colonization
.png){kind=icon}
OA
AI
DOI：10.1128/CMR.00021-17.png)
.png){kind=icon}
.png){kind=icon}
分享.png){kind=icon}
收藏
摘要
En 中文
Clostridium difficile is the main causative agent of antibiotic-associated and health care-associated infective diarrhea. Recently, there has been growing interest in alternative sources of C. difficile other than patients with Clostridium difficile infection (CDI) and the hospital environment. Notably, the role of C. difficile-colonized patients as a possible source of transmission has received attention. In this review, we present a comprehensive overview of the current understanding of C. difficile colonization. Findings from gut microbiota studies yield more insights into determinants that are important for acquiring or resisting colonization and progression to CDI. In discussions on the prevalence of C. difficile colonization among populations and its associated risk factors, colonized patients at hospital admission merit more attention, as findings from the literature have pointed to their role in both health care-associated transmission of C. difficile and a higher risk of progression to CDI once admitted. C. difficile colonization among patients at admission may have clinical implications, although further research is needed to identify if interventions are beneficial for preventing transmission or overcoming progression to CDI.
Keyword:
Clostridium difficile
health care-associated infections
intestinal colonization
AI总结
对已上传原文的论文进行重点信息的提取，主要内容包括：简要概述、研究摘要、背景介绍、关键亮点、图文解析、展望与总结。
期刊
IF:
19.3
论文数:
2.4K
被引数:
2.4W
机构
引用论文
Fabrication and properties of anisotropic polyimide aerogels with aligned tube‐like pore structure
PREAI
分享收藏Ichnology of Rhythmically Bedded Demopolis Chalk (Upper Cretaceous, Alabama): Implications for Paleoenvironment, Depositional Cycle Origins, and Tracemaker Behavior.png)
PALAIOS
PALAIOSIF0
PREAI
分享收藏Immunogenicity and protective efficacy of recombinant Clostridium difficile flagellar protein FliCOAAI
OAAI分享收藏
查看更多内容