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Underweight and mortality
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DOI：10.1017/S136898001500302X.png)
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Objective According to most prospective studies, being underweight (BMI<185 kg/m(2)) is associated with significantly higher mortality than being of normal weight, especially among smokers. We aimed to explore in a generally lean population whether being underweight is significantly associated with increased all-cause mortality. Design Prospective cohort study. Setting Korea Medical Insurance Corporation study with 14 years of follow-up. Subjects After excluding deaths within the first 5 years of follow-up (1993-1997) to minimize reverse causation and excluding participants without information about smoking and health status, 94 133 men and 48 496 women aged 35-59 years in 1990 were included. Results We documented 5411 (57 %) deaths in men and 762 (16 %) in women. Among never smokers, hazard ratios (HR) for underweight individuals were not significantly higher than those for normal-weight individuals (BMI=185-229 kg/m(2)): HR=087 (95 % CI 041, 184, P=072) for underweight men and HR=112 (95 % CI 076, 165, P=058) for underweight women. Among ex-smokers, HR=086 (95 % CI 038, 193, P=072) for underweight men and HR=377 (95 % CI 042, 3229, P=024) for underweight women. Among current smokers, HR=160 (95 % CI 128, 201, P<0001) for underweight men and HR=207 (95 % CI 043, 994, P=036) for underweight women. Conclusions The present study does not support that being underweight per se is associated with increased all-cause mortality in Korean men and women.
Keyword:
Thinness
Mortality
Smoking
Obesity
Korea
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Association of All-Cause Mortality With Overweight and Obesity Using Standard Body Mass Index Categories A Systematic Review and Meta-analysis使用标准体重指数类别的全因死亡率与超重和肥胖的关联系统评价和荟萃分析OAAI
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