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Urine albumin-creatinine ratio as a predictor of kidney function decline in alport syndrome
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DOI：10.1093/ckj/sfag191.png)
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Abstract
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Chronic kidney disease (CKD) significantly impacts health and lifespan, but its progression remains difficult to predict. Therefore, there is a need for biomarkers to identify patients at risk of a rapid decline in kidney function. Alport syndrome (AS) exemplifies this challenge, as some patients experience rapid progression, others exhibit a more gradual decline in kidney function. We hypothesized that urinary proteins, such as albumin, Immunoglobulin G (IgG) or alpha-1-microglobulin could serve as predictors of kidney function decline.
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