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摘要
En 中文
Vancomycin is a glycopeptide antibiotic that is active against staphylococci, streptococci, and other gram-positive bacteria. It is the drug of choice for the treatment of infections due to methicillin-resistant staphylococci, Corynebacterium jeikeium, and multiply resistant strains of Streptococcus pneumoniae, Vancomycin is an alternative treatment for serious staphylococcal and streptococcal infections, including endocarditis, when allergy precludes the use of penicillins and cephalosporins, It is bactericidal against most strains of staphylococci and nonenterococcal streptococci and is rarely associated with serious toxicity, The recent emergence and increasing prevalence of vancomycin-resistant enterococci and rare strains of Staphylococcus aureus with intermediate vancomycin resistance pose a serious clinical threat because no other predictably effective therapy is available, These developments require a reassessment of the long-standing perception of vancomycin as a reliably effective agent against virtually ail gram-positive bacteria.
Keyword:
STAPHYLOCOCCUS-AUREUS
RENAL-FUNCTION
INTRAVENTRICULAR VANCOMYCIN
GLYCOPEPTIDE ANTIBIOTICS
PERITONEAL-DIALYSIS
INDUCED NEUTROPENIA
ORAL VANCOMYCIN
THERAPY
PHARMACOKINETICS
RESISTANT
期刊
IF:
6.7
论文数:
1.0W
被引数:
2.4W
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