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Vicarious trial and error

delete2016-02-19
delete296
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OA
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A. David Redish *
DOI:10.1038/nrn.2015.30delete
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摘要

摘要

En 中文
When rats come to a decision point, they sometimes pause and look back and forth as if deliberating over the choice; at other times, they proceed as if they have already made their decision. In the 1930s, this pause- and- look behaviour was termed `vicarious trial and error' ( VTE), with the implication that the rat was `thinking about the future'. The discovery in 2007 that the firing of hippocampal place cells gives rise to alternating representations of each of the potential path options in a serial manner during VTE suggested a possible neural mechanism that could underlie the representations of future outcomes. More- recent experiments examining VTE in rats suggest that there are direct parallels to human processes of deliberative decision making, working memory and mental time travel.
Keyword:
NUCLEUS-ACCUMBENS NEURONS
MEDIAL PREFRONTAL CORTEX
SPATIAL WORKING-MEMORY
PLACE-CELL SEQUENCES
DECISION-MAKING
ORBITOFRONTAL CORTEX
BEHAVIORAL FLEXIBILITY
DORSOMEDIAL STRIATUM
THETA OSCILLATIONS
VENTRAL STRIATUM

期刊

Nature Reviews Neuroscience 封面图
Nature Reviews Neuroscience
IF:
26.7
论文数:
4.0K
被引数:
4.8W

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