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Vitamin D: beyond bone
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DOI：10.1111/nyas.12129.png)
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In recent years, vitamin D has been received increased attention due to the resurgence of vitamin D deficiency and rickets in developed countries and the identification of extraskeletal effects of vitamin D, suggesting unexpected benefits of vitamin D in health and disease, beyond bone health. The possibility of extraskeletal effects of vitamin D was first noted with the discovery of the vitamin D receptor (VDR) in tissues and cells that are not involved in maintaining mineral homeostasis and bone health, including skin, placenta, pancreas, breast, prostate and colon cancer cells, and activated T cells. However, the biological significance of the expression of the VDR in different tissues is not fully understood, and the role of vitamin D in extraskeletal health has been a matter of debate. This report summarizes recent research on the roles for vitamin D in cancer, immunity and autoimmune diseases, cardiovascular and respiratory health, pregnancy, obesity, erythropoiesis, diabetes, muscle function, and aging.
Keyword:
vitamin D
cancer
immunity
pregnancy
obesity
diabetes
pulmonary disease
muscle
aging
cognitive function
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引用论文
Cardiomyocyte-Specific Deletion of the Vitamin D Receptor Gene Results in Cardiac Hypertrophy心肌细胞特异性维生素d受体基因缺失导致心脏肥大.png)
CIRCULATIONOAAI
CIRCULATIONIF38.6
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OAAI
OAAI分享收藏Weight Loss Is Associated With Increased Serum 25-Hydroxyvitamin D in Overweight or Obese WomenOBESITYOAAI
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