Warhead assembly in a lethal pathogen

Elijah Abraham

doi:10.1038/s41557-022-01013-z

2022-07-29

PRE

Elijah Abraham

Rebecca A. Butcher *

DOI：10.1038/s41557-022-01013-z

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摘要

En 中文

Malleicyprols are highly reactive polyketides responsible for virulence in some pathogenic bacteria. Now, the enzyme that constructs the cyclopropanol warhead of malleicyprols has been identified. This enzyme could represent a useful target for developing new antivirulence therapeutics.

期刊

Nature Chemistry

IF:

20.2

论文数:

4.4K

被引数:

4.8W

机构

State University System of Florida

学者数:

12.8W

论文数: 10.9W

被引数: 130

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