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3D-printed microneedles for oral and periodontal drug delivery: Design principles, biofabrication strategies, and translational perspectives

delete2026-08-04
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PRE
AI
T
Tuba Bedir
O
Oğuzhan Gündüz *
C
Cem Bülent Ustündag
DOI：10.1016/j.bioadv.2026.215096delete
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Abstract

Abstract

En 中文
• Critically reviews 3D-printed MNs for oral and periodontal drug delivery. • Demonstrates how additive manufacturing enables customized MN platforms. • Summarizes biomaterials, fabrication methods, and therapeutic applications. • Identifies key barriers to the clinical translation of oral MN systems. • Highlights emerging trends in smart, bioresponsive, and AI-assisted MN technologies.
Keywords:
Microneedles
Oral drug delivery
Periodontitis
3D printing
Additive manufacturing
Periodontal regeneration
Immunomodulation

Journal

Biomaterials Advances cover
Biomaterials Advances
IF:
6
Papers:
1.9K
Citations:
6.0K

Organization

M
marmara university
Scholars:
1.8K
Papers: 798
Citations: 0
Y
Yildiz Technical University
Scholars:
5.4K
Papers: 5.2K
Citations: 42
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