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5-Aminolevulinic Acid-Induced Fluorescence-Guided Margin Mapping and Slow Mohs Surgery for Localized Extramammary Paget Disease: A Retrospective Exploratory Comparative Study
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DOI：10.1016/j.pdpdt.2026.105564.png)
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Abstract
En 中文
Extramammary Paget disease (EMPD) often extends beyond its clinically visible borders, making surgical margin control difficult, particularly in anatomically sensitive regions. This retrospective exploratory study compared 5-aminolevulinic acid (5-ALA)-induced fluorescence-guided margin mapping with slow Mohs surgery for localized EMPD, with emphasis on final margin clearance, treatment-process efficiency, tissue preservation, reconstruction requirement, patient-reported satisfaction, and crude recurrence proportion.
Keywords:
extramammary Paget disease
5-aminolevulinic acid
fluorescence-guided surgery
slow Mohs surgery
surgical margins
functional preservation
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