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A 3D-printed diffusion cell for nail permeation testing
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DOI：10.1016/j.ijpharm.2026.126898.png)
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Abstract
En 中文
• Evaluating nail API diffusion is essential for antifungal development but hindered by costly or inaccessible models. • A novel 3D-printed cell and bovine hoof model was developed to assess API diffusion. • Formulations were tested over 7 days in the 3D-printed system. • The amount of drug recovered in the hoof slices increased between day 2 and day 7, demonstrating the model’s ability to describe diffusion kinetics.
Keywords:
3D printing
nail permeation
antifungal drug delivery
diffusion kinetics
bovine hoof model
Journal
IF:
5.2
Papers:
2.2W
Citations:
6.7W