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A copper nanocluster-mediated trimodal PLLA scaffold: Cascade photo-themal-Fenton catalysis for biofilm removal and antibacterial storm

delete2026-04-11
delete0
PRE
AI
F
Fangwei Qi
Z
Zhongxing Zou
X
Xiaojuan Guo
H
Huixing Li
X
Xiuwen Gao
D
Dongan Wang
S
Shuping Peng *
C
Cijun Shuai *
DOI：10.1016/j.jphotochem.2026.117257delete
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Abstract

Abstract

En 中文
• Proposes a safe and efficient strategy against implant-associated infections by combining PTT and PDT without antibiotics. • Develops an antibacterial PLLA scaffold by incorporating Cu nanocluster-anchored g-C3N4 nanosheets via SLS. • Demonstrates PDT effect disrupts biofilms, while enhanced PTT and Fenton-like reactions synergistically boost ROS generation. • Shows outstanding antibacterial efficacy, achieving high inhibition rates of 97.8% against E. coli and 98.9% against S. aureus.
Keywords:
antibacterial scaffold
photothermal therapy
photodynamic therapy
biofilm removal
copper nanoclusters

Journal

J
journal of photochemistry and photobiology a: chemistry
IF:
0
Papers:
301
Citations:
1

Organization

C
Central South University
Scholars:
10.0W
Papers: 7.2W
Citations: 10.9W
J
Jiangxi University of Science and Technology
Scholars:
3.6K
Papers: 1.2K
Citations: 7.2K
C
Chinese University of Hong Kong
Scholars:
3.4W
Papers: 3.2W
Citations: 5.6W
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