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A data-driven algorithm to determine 1H-MRS basis set composition

delete2025-08-16
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OA
AI
C
Christopher W. Davies‐Jenkins
H
Helge J. Zöllner
D
Dunja Simičić
Ş
Şeyma Alçiçek
R
Richard A.E. Edden
G
Georg Oeltzschner *
DOI:10.1002/mrm.70030delete
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Abstract

Abstract

En 中文
Metabolite amplitude estimates derived from linear combination modeling of MR spectra depend on the precise list of constituent metabolite basis functions used (the “basis set”). The absence of clear consensus on the “ideal” composition or objective criteria to determine the suitability of a particular basis set contributes to the poor reproducibility of MRS. In this proof-of-concept study, we demonstrate a novel, data-driven approach for deciding the basis-set composition using Akaike information criteria (AIC).
Keywords:
2HG
basis set
cystathionine
information criteria
magnetic resonance spectroscopy
model selection

Journal

Magnetic Resonance in Medicine cover
Magnetic Resonance in Medicine
IF:
3
Papers:
1.2W
Citations:
3.1W

Organization

G
Goethe University
Scholars:
319
Papers: 138
Citations: 0
J
Johns Hopkins University School of Medicine
Scholars:
2.1K
Papers: 748
Citations: 2