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A diffusion barrier limits nuclear leaks

delete2023-10-02
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PRE
AI
H
Hiral Shah
G
G.K. Dey *
DOI:10.1038/s41556-023-01243-4delete
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Abstract

Abstract

En 中文
ESCRT-III seals holes in the nuclear envelope (NE). A study now shows that the Cmp7-directed ESCRT-III cascade that grommets and reseals NE holes after spindle pole body (SPB) extrusion at the end of fission yeast mitosis is complemented by the presence of a proteinaceous diffusion barrier to ensure NE integrity.

Journal

Nature Cell Biology cover
Nature Cell Biology
IF:
19.1
Papers:
6.1K
Citations:
4.8W

Organization

E
european molecular biology laboratory (embl)
Scholars:
8.3K
Papers: 5.1K
Citations: 31